Managing protein in the gut :
The benefits for poultry production

The Jefo Protease has been designed to enhance the management of feed protein flow in poultry. It aids in reducing feed costs, allows the use of alternative protein sources, and promotes improved intestinal integrity.


Is It More Than Amino Acids Release?

November 7, 2023

10:00 a.m. (GMT-5)

With Dr. Ludovic Lahaye

Why Do Protein and Amino Acids often Limit Performance?

Effective protein management in poultry diet is vital for optimal production. However, numerous factors can influence actual protein intake, resulting in high variability.

Feed/Raw materials

  • Cost/Prices variability
  • Availability of synthetic amino acids
  • Valorization of local sources


  • Digestibility variability: age, transit time, health, etc.
  • Evaluation of amino acids requirements: impact of immunity, gut restructuring, etc.


  • Ability to use non-digestible protein:
    bad fermentation, alteration of gut integrity, ammonia production

This significant variability can often limit zootechnical performance.

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Managing Feed Protein Flow: A Crucial Challenge

To manage feed protein flow effectively, it’s necessary to act on the digestible protein fraction, releasing oligopeptides absorbed by the bird for better performance. It’s also crucial to control the non-digestible protein fraction, which can be used by pathogenic bacteria, affecting intestinal integrity.

Small Intestine

Digestible Protein

Maintenance and growth

Meat and egg production

Digestible Protein

Maintenance & growth

Meat and egg production


Non Digestible Protein

Fermentation in the caecum/hindgut > inflammatory metabolites

Intestinal Integrity

Non Digestible Protein

Fermentation in the caecum/hindgut > inflammatory metabolites

Intestinal Integrity

The Jefo Protease helps lower protein content in the poultry gut, reducing feed costs and ensuring secure performance.

Our solution’s main benefits

Better Use of Digestible Protein in the Gut to Lower Feed Cost

Optimal protein digestion in the small intestine reduces feed costs while maintaining superior performance.

Cost savings

  • The Jefo Protease improves feed optimization
  • The reduction of needed and wasted protein equals lower feed cost

Get the best results from your feeding strategy with Jefo Protease

  • A safety net for raw material quality variability
  • A versatile product for efficient use in your feed programs with personalized recommendations based on bird type, diet, and protein levels

Jefo has developed a specific tool to define the best recommendations per animal species and raw materials context.

Contact us to define your own application and potential savings!

Jefo is using an innovative methodology to assess intestinal integrity.

Contact us to know more about
our unique evaluation tool!

Lower Non-Digestible Protein in the Gut to Improve Intestinal Integrity

The Jefo Protease optimizes feed assimilation in the small intestine, reducing indigestible protein content in the hindgut.

Lowered nitrogen waste, resulting in:

  • Reduced environmental impact
  • Improved air quality and lung health
  • Enhanced litter quality leading to reduced pododermatitis incidence

Reduces the indigestible portion of feed ingredients that favor bacteria growth

Lowers the protein content in the feeds: a way to help during heat stress challenges

Watch the Webinar | Managing protein in the gut

Get the best results from your feeding strategy with Jefo Protease

With Dr. Elizabeth Santin, Emmanuel Landeau and Anouk Cottin-Tillon

Contact us directly or talk to an expert